The study was conducted by researchers at Stanford University (Getty Stock)
Specifically, 81 percent of the California cohort experienced notable changes at the ages of 44 and 60.
Professor Michael Snyder, a geneticist who directs the Center for Genomics and Personalized Medicine at Stanford and is the study’s senior author, stated, “We don’t just gradually age. There are some profound changes.”
He noted that the mid-40s and early 60s are periods of significant transformation across various molecular classes.
Snyder emphasized, “I strongly believe we should consider lifestyle adjustments while we are still in good health.”
44-year-olds were found to experience a spike in the ageing process (Getty Stock)
Many changes noted around these ages were associated with heart health and a decrease in participants’ capacity to process caffeine.
Additionally, those aged 44 and 60 exhibited elevated blood sugar levels, and proteins linked to atherosclerosis—a buildup of fats and cholesterol in artery walls—were increasingly identified.
While the aging shift at 44 often aligns with those who have uteruses beginning perimenopause, one expert suggests there are “likely other” factors influencing this transition.
Dr. Xiaotao Shen, a former post-doctoral at Stanford Medical School and the study’s primary author, remarked, “Though menopause or perimenopause may play a role in changes for women in their mid-40s, there are probably other, more significant factors affecting both genders.”
Featured Image Credit: Getty Stock Image
